NCERT Class 12 Biology Chapter 5 Molecular Basis of Inheritance MCQs & PYQ

In NCERT Class 12 Biology Chapter 5, titled "Molecular Basis of Inheritance," students explore the molecular mechanisms behind inheritance. The chapter covers the structure and function of DNA, RNA, and the process of protein synthesis. It also discusses the concept of gene expression, replication, transcription, and translation. Additionally, students learn about the genetic code, mutations, and the central dogma of molecular biology, providing a solid foundation for understanding genetics at a molecular level.
This article provides a comprehensive resource for exam preparation. It includes sample MCQs and subjective questions for CBSE and CUET, alongside downloadable PDFs of Class 12 Biology Chapter 5 MCQs and previous year questions for detailed practice of NCERT Class 12 Molecular Basis of Inheritance.
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Class 12 Biology Chapter 5 MCQs
This question bank includes previous years' CUET and CBSE MCQs, along with questions curated by subject experts. Below are 5 sample multiple-choice questions (MCQs) for Class 12 Biology Chapter 5: Molecular Basis of Inheritance. For the full set of 50 questions, download the PDF using the link provided below.
1.
Central dogma in molecular biology states that genetic information flows from:
(a) DNA → DNA → Lipid      (b) DNA → mRNA → Protein
(c) Protein → mRNA → DNA (d) DNA → Protein → mRNA
2.
Identify the flow of information according to the ‘Central Dogma’ of Molecular biology:
(a) mRNA → Protein → DNA (b) mRNA → tRNA → RNA
(c) DNA → mRNA → Protein (d) Protein → mRNA → DNA
3.
Adenine pairs with Thymine through how many hydrogens bonds?
(a) 2     (b) 3     (c) 4     (d) 5
4.
Identify the statements true for RNA.
(A) RNA acts as a genetic material for some viruses.
(B) RNA also functions as an adapter molecule.
(C) RNA has hexose sugar as its backbone.
(D) RNA also acts as catalyst in some cases.
Choose the correct answer from the options given below:
(a) (A), (B) and (C) only          (b) (A), (B) and (D) only
(c) (B), (C) and (D) only          (d) (A), (C) and (D) only
5.
Arrange the following steps of experiments performed by Griffith in correct series.
(A) 'S' strain → injected into mice → Mice died
(B) 'S' strain (Heat killed) → injected into mice → Mice lived
(C) 'R' strain → injected into mice → Mice lived
(D) 'S' strain (Heat killed) + 'R' Strain (Live) → injected into mice → Mice died
Choose the correct answer from the options given below:
(a) (A), (B), (C), (D)    (b) (B), (A), (C), (D)    (c) (B), (C), (D), (A)    (d) (A), (C), (B), (D) 
Class 12 Biology Chapter 5 Subjective Questions Without Solutions
This question bank includes previous years' CBSE subjective questions (2 marks and above) without solutions, along with expert-curated questions. Below are 5 sample subjective questions for Class 12 Biology Chapter 5: Molecular Basis of Inheritance. To access all questions, download the PDF from the link provided below.
1.
A segment of DNA molecule comprises of 546 nucleotides. How many cytosine nucleotides would be present in it if the number of adenine nucleotides is 96?
(CBSE 2019, 2M)
2.
The length of DNA in any cell is far greater than the dimension of its nucleus. Explain how this enormous DNA is packaged in a eukaryotic cell.
(CBSE 2023, 3M)
3.
Explain the discovery made by Hershey and Chase using radioactive sulphur and phosphorus in their experiment. 
(CBSE 2020, 3M)
4.
Hershey and Chase carried out their experiment under three steps :
(a) Infection,   (b) Blending, and         (c) Centrifugation. 
Explain each one of these steps that helped them to prove that DNA is the hereditary material.
(CBSE 2019, 3M)
5.
Describe the experiment carried out by Hershey and Chase. Write the conclusion they arrived at.
(CBSE 2020, 5M)
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Sub Areas of Chapter 5: Molecular Basis of Inheritance
Chapter Name
Sub Topics
Molecular Basis of Inheritance
5.1 Introduction
5.2 Structure of DNA and RNA
5.3 Replication of DNA
5.4 Transcription and its Regulation
5.5 Translation and its Mechanism
5.6 Genetic Code
5.7 Mutations
5.8 Gene Expression and Regulation
Review of NCERT Class 12 Biology Chapter 5
In NCERT Class 12 Biology Chapter 5, "Molecular Basis of Inheritance," students dive into the molecular mechanisms that govern genetic inheritance. The chapter introduces the structure and function of nucleic acids, the process of DNA replication, and the role of RNA in protein synthesis. Key concepts like transcription, translation, and the genetic code are explored, along with the causes and effects of mutations. This knowledge is foundational for understanding genetic variations, inheritance patterns, and the molecular underpinnings of various biological processes.
By practicing MCQs and subjective questions, students can strengthen their comprehension of molecular genetics. Mastery of this chapter is essential for students aiming to pursue careers in genetics, biotechnology, and related fields.
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